My old college roommate had some great ones, though the most memorable were the ones that didn't work.

We were at a dance club and he went up to a girl and asked if she wanted to dance. She said no. He then yelled, I don't think you heard me! I said, You look fat in those pants!" Everybody died laughing.

Another night after a girl gave him the cold shoulder I heard him tell her, " I don't understand why with such beautiful blonde hair that you dye your roots so dark." Needless to say that didn't go over well. But, there is a lot you can say at 6'3" and 270 lbs when your in good shape.