My experience over a span of about 25 years:

Loc-on-
1. Lots of work. Anybody that says they can do it quick is being dishonest. Lots of work. Did I say lots of work? LOL
Why anyone would take in a loc-on and steps/ladder the morning of the hunt is beyond me.
2. Tiny platform. If you can't pull your bow back from a seated position, or stand totally erect and pull it back without fear of losing your balance, do NOT use a loc on.
3. Absolutely limited. I don't hunt anywhere that the deer ALWAYS come within bow range of that tree, or at least where they do it for very long. Acorns go away, seasonal patterns move the deer, etc. Lots of work for a small window.
4. In the end I've just never had enough reward for the labor involved. I quit hanging them years and years ago.
5. There will ALWAYS be a huge hairy spider in a funnel web inside the tube against the tree. Good luck when you climb up there in the dark and see him crawl back down that tube, then you know you gotta sit on him all morning.
6. You WILL forget your seat cushion every time.
7. Lastly, they are lots of work.