I shot two does (85 lbs and 90 lbs) last year each at 120 and 150 yards respectively with the 6.5 143 ELD-X out of a 26" Criterion over 41.8 gr H4350 going right at 2750 fps. Both broadside shots that liquefied the heart and lungs and dropped both in the tracks.

Also worth noting, the 6.5 Grendel 123 ELD match factory ammo worked fine on two other does at my uncle's place in Florida for me last year. Both were roughly 85 lbs and they both went less than 10 yards. Again, lungs and heart were toast