Shot a mule deer doe last week at 323 yards in center of the neck, and I was actually aiming there! I've shot animals at longer distances in the body, but that was the best semi-long range shot. Shot 9 more mule deer does on the same trip last week, and all of those were under 200 yards, seven of them neck/head shots.
Longer shots were custom 300WM, shorter were suppressed 308 M700. Yes, it was legal there. No, it wasn't game fenced.