All four number one seeds making it to the final four, has only happened once in history. I think chances of that are slim. If I had to pick two that I wouldn't think would make final four, it would probably be auburn and Houston. Florida looks the best, but I got a gut feeling they don't make it. So that just leaves Duke and an upsetter. Upsetter won't upset twice, so my pick would be Duke to win it all. But I still hope auburn proves me wrong!