I would think 300win mag and a 308 should pretty well have you covered. Since you reload, it is nice to have 2 guns that both use .308 projectiles. 300 winmag is good for everything in North America and more and is pretty flat shooting. I would probably have the win mag custom built or maybe a Christensen Arms Ridgeline titanium. For the 308 I would get something nice and lite with a 20" or 18” carbon wrapped barrel also maybe in CA Ridgeline titanium or custom. Can handload the 308 full power or even reduced power loads or even subsonic for whatever purpose you need. To mix things up even more I would maybe even get the 308 in a BLR levergun. I have a soft spot for lever guns. I would even go as far as to say 300 win mag and 30-30. One new gun with new technology and one just classic, fast handling, and proven lever gun. Both using .308 projo's.