I have always shot right handed even though I am left eye dominant. A couple of years ago I started having issues with my left shoulder and was having a lot of pain trying to hold the bow in my left hand and shoot right handed. So I figured what the heck, I’ll give it a try. Bought an inexpensive left handed bow and when I shot the first time it felt really weird. After that it started feeling natural. Now It is second nature to shoot a bow left handed. Funny side story, the first deer I shot with left handed bow, my shot was WAY off until I realized that during the excitement of the moment I was still shooting left handed but had aimed with my right eye. Doh!, Anyway, I would strongly encourage someone that is cross eye dominant to at least give shooting with your dominant eye a try. You may discover that you are a much better shot shooting with that dominant eye.