Shot at and missed a 135 class buck on Saturday and it was blowing 20 plus. Also saw a six and a nice 110" 8 point. Earlier in the year I was sitting in a different stand and saw a 125 class buck and the wind was blowing 15-20. I couldn't get a bead on him. Your answer in short is YES. It will do a number on your mind but sit it out. It bothers us more than it does them.