Both of my kids killed their first deer with a a-bolt 22-250. I've killed everything that walks or flys with it. With the right ammo it is deadly. I used to shoot trophy bonded but went to the 60gr nosler partition. The 55gr remington stuff is good also. I know I just opened up a can of worms but now a days bullets can hold up at that speed and give pass through every time. If I had to just have one rifle it would be a 22-250. My dad has killed some fine bucks with 60gr hornadys out of a 223. I know Im not alone in this.
