Wow.
First thing I would do is look at my rifle. For example if your shooting a TC Encore and have a Hammer Extender installed on it, the problem could very well be the rifle not the ammo. Or it could still yet be head space on the rifle as well. The likelyhood of misfire of that many rounds is much more likely the rifle than the ammo even though it is Remington Brand Ammo.
I am not a Remington Ammo fan at all. Shoot a box of any other brand of ammo through a rifle then clean it, then shoot a box of Remington Ammo through a Rifle and Clean it. You'll get the picture.