I would buy a 280 Ackley or a 7mm Backcountry instead, if you want the same horsepower with lower recoil.
If she's only shooting whitetails, buy a 7mm-08 and run Barnes 120 grain TTSX. Deer won't know the difference inside 300 yards, but your wife sure will.
Ruger chambers the American in 7mm-08, as do a dozen other rifle companies. One of our favorite whitetail cartridges. My wife and I have killed a pile with 7mm-08. I go play with other calibers, but I never leave the 7-08. Just bought a new one for myself 2 weeks ago. I think that one makes about 15 that have lived here for a few days or more.