IMO, it comes down to how you use it and if you reload or not.
the 7prc definitely has more HP than the 280ai and factory ammo is more available and is optimized for the heaviest, high BC bullets. It does require a larger magnum action and youll only get 2-3 rounds in a magazine.
280ai is a Goldilocks round IMO as far as speed/performance/recoil but not as much factory ammo available and in general is optimized for bullets in the 145-160 weight class, you'll get 4-5 rounds in most magazines and you can use a slimmer standard action but I wouldnt reccomend it to anyone who doesn't reload.
