I hunt with a 2x7 that I feel comfortable out to 350 with. I do have a 4-14 on a 300 win mag that I have never hunted with. But, the 14 power is capable to shoot farther than I ever will. My ling range friends that shoot 1000 yards only use 14 power and I dont plan to ever shoot at an animal that far away.
I hunt mostly between 2-4 power. If I think my shots will be 100+ I leave it on 4 power.