The 17 and 22mag are supersonic and all you'll lose is the muzzle blast. The same is true for your 22 if you don't shoot subsonic ammo. CCI Standard Velocity is very good 22 ammo and stays subsonic. POI usually changes when you add a suppressor. How much varies depending on the suppressor and the host.
I will add that in today's suppressor market the better known manufacturers are building state of the art suppressors. It's truly a market where you "get what you pay for". FRP is one of the most notable area where this is noticeable.
